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Herceptin: Mechanism of action

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For more information, visit CancerQuest at http://www.cancerquest.org/drugs/trastuzumab. The anti-cancer drug Herceptin (trastuzumab) is an antibody that binds to cancer cells over-expressing the Her2/neu receptor. Activation of the Her2/neu receptor leads to cell proliferation. The animation shows one possible way that the drug can work, by blocking signals from being sent from the receptor into the cells. For further information, visit http://www.cancerquest.org

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