For an appointment at the Mayo Clinic Women’s Health Clinic, please call 1-507-538-3270 or visit, and specify the Women’s Health Clinic. Vaginal dryness is a common complaint in women and is due to hormonal changes in perimenopause and menopause. Treatment may be straightforward, but also may be complicated by biological, psychological, relationship, and sociocultural factors. Several treatment options are available. Women’s Sexual Pain – Vulvar Pain –