The reason those eating plant-based diets have less fat buildup in their muscle cells and less insulin resistance may be because saturated fats appear to impair blood sugar control the most. Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ This is the third of a 3-part series, starting with What Causes Insulin Resistance? (http://nutritionfacts.org/video/What-Causes-Insulin-Resistance) and The Spillover Effect Links Obesity to Diabetes (www.nutritionfacts.org/video/the-spillover-effect-links-obesity-to-diabetes). I wish I could have fit it all into one video, but it would have just been too long. Even if saturated fat wasn’t associated with heart disease, the effects on pancreatic function and insulin resistance in the muscles would be enough to avoid it. Despite popular press accounts, saturated fat intake remains the primary modifiable determinant of LDL cholesterol, the #1 risk factor for our #1 killer heart disease. See The Saturated Fat Studies: Buttering Up the Public (http://nutritionfacts.org/video/the-saturated-fat-studies-buttering-up-the-public/) and The Saturated Fat Studies: Set Up to Fail (http://nutritionfacts.org/video/the-saturated-fat-studies-set-up-to-fail/). How low should we shoot for in terms of saturated fat intake? As low as possible, according to the U.S. National Academies of Science Institute of Medicine: Trans Fat, Saturated Fat, and Cholesterol: Tolerable Upper Intake of Zero (http://nutritionfacts.org/video/trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero/). Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/lipotoxicity-how-saturated-fat-raises-blood-sugar/ and he’ll try to answer it! Image Credit: Djjewelz and Max Westby via Flickr, Kapa65 and WaltiGoehner via Pixabay, and Ljupco Smokovski via 123RF. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org