(USMLE topics) Molecular basis of the sliding filament theory (skeletal muscle contraction) – the cross bridge cycle. This video is available for instant download licensing here : https://www.alilamedicalmedia.com/-/galleries/all-animations/bones-joints-and-muscles-videos/-/medias/79b11851-3cbe-4df2-921d-3c55818a6c83-muscle-contraction-the-cross-bridge-cycle-narrated-animation Voice by: Sue Stern ©Alila Medical Media. All rights reserved. Support us on Patreon and get FREE downloads and other great rewards: patreon.com/AlilaMedicalMedia Muscle contraction is at the basis of all skeletal movements. Skeletal muscles are composed of muscles fibers which in turn are made of repetitive functional units called sarcomeres. Each sarcomere contains many parallel, overlapping thin (actin) and thick (myosin) filaments. The muscle contracts when these filaments slide past each other, resulting in a shortening of the sarcomere and thus the muscle. This is known as the sliding filament theory. Cross-bridge cycling forms the molecular basis for this sliding movement. – Muscle contraction is initiated when muscle fibers are stimulated by a nerve impulse and calcium ions are released. – To trigger muscular contraction, the troponin units on the actin myofilaments are bound by calcium ions. The binding displaces tropomyosin along the myofilaments, which in turn (and) exposes the myosin binding sites. – At this stage, the head of each myosin unit is bound to an ADP and a phosphate molecule remaining from the previous muscular contraction. – Now, the myosin heads release these phosphates and bind to the actin myofilaments via the newly exposed myosin binding sites. – In this way, the actin and myosin myofilaments are cross-linked. – The two myofilaments glide past one another, propelled by a head-first movement of the myosin units powered by the chemical energy stored in their heads. As the units move, they release the ADP molecules bound to their heads. – The gliding motion is halted when ATP molecules bind to the myosin heads, thus severing the bonds between myosin and actin. – The ATP molecules bound to myosin are now decomposed into ADP and phosphate, with the energy released by this reaction stored in the myosin heads, ready to be used in the next cycle of movement. – Having been unbound from actin, the myosin heads resume their starting positions along the actin myofilament, and can now begin a new sequence of actin binding. – Thus, the presence of further calcium ions will trigger a new contraction cycle

Muscle Contraction – Cross Bridge Cycle, Animation.
- Post author:
- Post published:June 14, 2021
- Post category:Uncategorized
- Post comments:0 Comments
You Might Also Like

Biceps: One Arm Preacher Curl Low Pulley Cable

ECG basics 7/10 – Determining Normal Sinus Rhythm

What is the Liver and what does it do – LANDED Peer Education Service

What are the commonest causes of Anemia? – Dr. Satish Kumar

Health | Diabetes What is diabetes | Health articles

Child And Adolescent Psychiatry Video – 2

What to Eat before Bed to Build Muscle | Bodybuilding Diet

Semen Analysis – What is the normal sperm count? | Metromale Clinic & Fertility Center

How To Build Big Biceps / Guns / Arms – Buff Dudes

Endocrine System Diabetes And Asanas Video – 2

Supplements -Muscle -Training -Fitness -Nutrition & ALL Health

6 Nutritional Foods And Diet For Rheumatoid Arthritis

Get Pregnant Fast with Unexplained Infertility

Minerals – What Are Minerals – What Do Minerals Do – What Are The Essential Minerals

Leg Raises-2

“Complete Blood Count (CBC) Test” by getLABtested.com

Does BMI Actually Matter?

MINOXIDIL WORK ON TEMPLES IN JUST 2 MONTHS??!

Fat Loss, Weight Loss Video – 27

Anaerobic – Medical Definition
Blood Sugar Testing
One Arm Row Dumbbell-8

BTEC PE – Circuit Training
One Arm Row Dumbbell-2

Food Guide Pyramid Video – 2

Human Body, Body Building Muscle Building Anatomy Physiology Video – 44

Fever In Children & Adults – Natural Remedies to bring down the temperature

What is LACTATION ROOM? What does LACTATION ROOM mean? LACTATION ROOM meaning & explanation

How to Inject HGH Demonstrated by Dr. Robert Carlson

Energy Food Metabolism

Rugby Video – 2

Kidney Function Tests (KFT) – An Overview

Advanced Hammer Curl Tip – For Bigger Arms

Genetics and Genetics Testing

Digestion and Absorption of Carbohydrates PART 1/2 – Carbohydrate Metabolism – Glucose Metabolism

What Is Vitamin B12? | Vitamins

What Is A Mineral?

How to Perform a Back Extension | Exercise Form Video

Pre Blended Creams Video – 3

HGH, Growth Hormones & Plant Hormones Video – 23

Barbell Decline Bench Press – HASfit Lower Chest Exercise Demonstration – Decline Press – Pectoral
