(USMLE topics) Molecular basis of the sliding filament theory (skeletal muscle contraction) – the cross bridge cycle. This video is available for instant download licensing here : https://www.alilamedicalmedia.com/-/galleries/all-animations/bones-joints-and-muscles-videos/-/medias/79b11851-3cbe-4df2-921d-3c55818a6c83-muscle-contraction-the-cross-bridge-cycle-narrated-animation Voice by: Sue Stern ©Alila Medical Media. All rights reserved. Support us on Patreon and get FREE downloads and other great rewards: patreon.com/AlilaMedicalMedia Muscle contraction is at the basis of all skeletal movements. Skeletal muscles are composed of muscles fibers which in turn are made of repetitive functional units called sarcomeres. Each sarcomere contains many parallel, overlapping thin (actin) and thick (myosin) filaments. The muscle contracts when these filaments slide past each other, resulting in a shortening of the sarcomere and thus the muscle. This is known as the sliding filament theory. Cross-bridge cycling forms the molecular basis for this sliding movement. – Muscle contraction is initiated when muscle fibers are stimulated by a nerve impulse and calcium ions are released. – To trigger muscular contraction, the troponin units on the actin myofilaments are bound by calcium ions. The binding displaces tropomyosin along the myofilaments, which in turn (and) exposes the myosin binding sites. – At this stage, the head of each myosin unit is bound to an ADP and a phosphate molecule remaining from the previous muscular contraction. – Now, the myosin heads release these phosphates and bind to the actin myofilaments via the newly exposed myosin binding sites. – In this way, the actin and myosin myofilaments are cross-linked. – The two myofilaments glide past one another, propelled by a head-first movement of the myosin units powered by the chemical energy stored in their heads. As the units move, they release the ADP molecules bound to their heads. – The gliding motion is halted when ATP molecules bind to the myosin heads, thus severing the bonds between myosin and actin. – The ATP molecules bound to myosin are now decomposed into ADP and phosphate, with the energy released by this reaction stored in the myosin heads, ready to be used in the next cycle of movement. – Having been unbound from actin, the myosin heads resume their starting positions along the actin myofilament, and can now begin a new sequence of actin binding. – Thus, the presence of further calcium ions will trigger a new contraction cycle

Muscle Contraction – Cross Bridge Cycle, Animation.
- Post author:
- Post published:June 16, 2021
- Post category:Uncategorized
- Post comments:0 Comments
You Might Also Like

Cable V Bar Preacher Curls

What are proteins made up of?

Ophthalmology Video – 4

Ornithine During Liver Flush

Echocardiogram (Echo)

Practical Demo of Bone Mineral Density (BMD) (Hindi) (720p HD)

How To Do Perfect SQUAT | FITNESS SPECIAL | SQUATS For Beginners | WORKOUT VIDEO

Reproductive embryology

StairMaster HIIT Programming Solutions

Exocrine Gland and Endocrine Glands

How I Hit My Upper Chest Without Any Incline Presses

Top 10 Best Vitamin B-Complex Supplements

Decline Bench Press-4

SEATED ROW MACHINE for BACK! (Hindi / Punjabi)

1 & 2 Weeks Pregnant: What You Really Need to Know
Lat Pull Down-8

Angioplasty Procedure Animation Video.

Diabetes :- Causes,Types & Treatment ! (Award Wining Presentation)

Lat Pull Down-12

Nephrology Video – 1

blood sugar chart

8 Signs You May Have a Thyroid Problem

Fasting + Post Meal Blood Sugar Readings

Keto Diet, Keto Foods, Keto Recipes Video – 8

What is Osteoporosis? – Dr. Anantharaman Ramakrishnan

If You Eat 2 Eggs at Breakfast For a Month, This is What Happens to Your Body

CDC Tuberculosis (TB) Transmission and Pathogenesis Video

The Human Body Video – 6

Are Glutamine supplements good?

Cardio-Thoracic Physiotherapy Video – 11

Branches of Physiotherapy Video – 17

What is BMI? – Understanding Body Mass Index

Andropause: Treating Male Hormone Imbalance Naturally (Male Menopause)

Reading 12-Lead ECG’s – EMTprep.com

The Difference Between Sperm & Semen – Episode 20

What is Aerobic Exercise- Cardio and aerobics workouts

THYROID HORMONES

How to Do a Crunch | Ab Workout

HAMMER CURLS- 5 DIFFERENT TYPES- Rich Piana

What is Type 1 Diabetes?

Shoulder Workout (Posterior Deltoid)
