Drug interactions occur on pharmacodynamic and pharmacokinetic levels. Examples of pharmacodynamic interactions are simultaneous administration of a NSAID and phenprocoumon (additive interaction), or of aspirin and ibuprofen (antagonistic interaction). Pharmacokinetic interactions occur at the levels of absorption (e.g., levothyroxine and neutralizing antacids), elimination (e.g., digoxin and macrolides), and metabolism, as in the competition for cytochrome P450 enzymes (e.g., SSRIs and certain beta-blockers). (See citation below) Second Channel ————————————————— ? USMLE Cases: https://www.youtube.com/channel/UCj6yv42uGIfGVI2IQqAvFNw Pocket Apps ————————————————— ? Pocket ECG https://play.google.com/store/apps/details?id=usmle.pass.basicecg ? Pocket Guidelines https://play.google.com/store/apps/details?id=com.talhahasanzia.threelevellistview ❤️ Pocket Heart Sounds https://play.google.com/store/apps/details?id=usmle.pass.heartsounds ? Pocket Lung Sounds https://play.google.com/store/apps/details?id=usmle.pass.lungsounds ? Pocket Labs https://play.google.com/store/apps/details?id=labs.reviews.labss ? Pocket Micro https://play.google.com/store/apps/details?id=com.bacterials.agarss ? Pocket OSCE https://play.google.com/store/apps/details?id=com.oscess.pess Topic References ————————————————— ?https://www.rxlist.com/drug-interaction-checker.htm ?https://www.fda.gov/drugs/resources-you-drugs/drug-interactions-what-you-should-know ?https://www.drugs.com/drug_interactions.html Description’s Citation ————————————————— Cascorbi I. Drug interactions–principles, examples and clinical consequences. Dtsch Arztebl Int. 2012;109(33-34):546-556. doi:10.3238/arztebl.2012.0546 Music Credit ————————————————— Title: Ticker by Silent Partner Title: Always Dreaming by Within Reach Title: Drift by Drift Software and Hardware ————————————————— Microphone: Blue Yeti X Professional Condenser Audio Software: Adobe Audition CC 2020 Video Software: Filmora-X and Adobe After Effects CS 6 Thumbnail Software: Adobe Photoshop CS 6 Join Us ————————————————— Instagram https://www.instagram.com/medical.pronunciations Twitter https://twitter.com/USMLEpass Whatsapp Study Group https://chat.whatsapp.com/J1QZFU5uCJAGQS8FikYzT6 Thanks for watching. You are awesome!
Drugs Interaction: Additive, Permissive, Synergistic, Tachyphylactic
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